Delta Sleep-Inducing Peptide (DSIP)

A sleep-related research peptide with old, small human studies and mixed results.

By

Peptide Dosing Library
Research & Education

Last reviewed

October 2026

25 nmol/kg

Older Human IV Trial Amount

100–300 mcg

Reported Community SC Amount

4–7 Nights

Older Human Trial Duration

6–14

Participants in Older Insomnia Trials
Delta Sleep-Inducing Peptide (DSIP)

DSIP

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OVERVIEW

Understanding DSIP

DSIP is a sleep-related research peptide studied in older, small human trials. Results have been mixed, and the routes and treatment windows used in those trials differ from contemporary subcutaneous community schedules.

Research Category

Sleep-related research peptide

Older Human Trial Route

Intravenous (IV)

Older Human Trial Amount

25 nmol/kg

Reported Trial Duration

Approximately 4–7 nights

Community-Reported Route

Subcutaneous (SC)

Reported Community Timing

Typically in the evening, 1–3 hours before sleep

Important Research Limitation

Older human trials used routes and treatment windows that differ from contemporary subcutaneous community schedules.

REPORTED PROTOCOLS

Reported DSIP Schedules

The following are reported human-trial and community-use examples from the source. Longer community schedules lack trial validation.

SC example

Per administration

Frequency

Daily total

Reported cycle

Older Human IV Trials

25 nmol/kg
Approximately 4–7 nights

Community SC Range 1

100–200 mcg
5–7 nights

Community SC Range 2

200–300 mcg
Four weeks or 6–8 weeks

Older Human IV Trials

Per administration

25 nmol/kg

Frequency

Daily total

Reported cycle

Approximately 4–7 nights

Community SC Range 1

Per administration

100–200 mcg

Frequency

Daily total

Reported cycle

5–7 nights

Community SC Range 2

Per administration

200–300 mcg

Frequency

Daily total

Reported cycle

Four weeks or 6–8 weeks
Community durations of four weeks and 6–8 weeks lack trial validation.

Research Context Only

Older human IV trials do not validate contemporary subcutaneous community schedules. Reported schedules should not be interpreted as established treatment guidance.

SAFETY

Safety & Reported Concerns

Available safety information is limited. Small studies cannot define the long-term safety profile of DSIP.

Reported concerns

Important Cautions

HANDLING & STORAGE

Storage & Handling Information

Storage Protection

Cold and light protection recommended by the source.

Mixed-Product Stability

Exact mixed-product stability must be verified.

Monitoring Considerations

Sleep timing and sleep quality.

Additional Monitoring

Daytime effects; dated compounding claims need rechecking.

CONCENTRATION WORKSHEET

DSIP Concentration Calculator

Example calculation values from the source. These are not mixing or administration instructions.

Amount (mg)

Final volume (mL)

Concentration (mg/mL)

Per 1 U (mcg)

Per 10 U (mcg)

10

2
5
50
500

Amount (mg)

10

Final volume (mL)

2

Concentration (mg/mL)

5

Per 1 U (mcg)

50

Per 10 U (mcg)

500

Amount (mg)

Final volume (mL)

Concentration (mg/mL)

Per 1 U (mcg)

Per 10 U (mcg)

U means a U-100 volume marking: 1 U = 0.01 mL. These values are calculation examples, not mixing or administration instructions.

CLINICAL EVIDENCE

What Human Studies Report

Older insomnia trials were small, often enrolling only 6–14 people. Some reported modest sleep improvements, while others did not differ meaningfully from placebo.

01

Small Human Trials

Older insomnia trials often included only 6–14 participants.

02

Mixed Sleep Outcomes

Some studies showed modest sleep improvements, while others did not differ meaningfully from placebo.

03

Limited Withdrawal Evidence

Withdrawal studies were methodologically limited.

REGULATORY INFORMATION

Regulatory & Research Status

Current Regulatory Check Required

The source notes that the page’s regulatory language is dated and requires a separate current check.
The source does not provide a current verified regulatory status for DSIP.